IMAGINE a world in which – instead of toxic solvents and chemicals – industrial manufacturing used sugar, starch and sunlight as inputs. Imagine products that biodegrade into utterly benign substances. Imagine pure, clean water leaving factories and polluted sources brought back to life. What if industrial chemicals were bio-based and generated by farmers practicing sustainable agriculture? Imagine a workplace free of “hazmat” gear, factories without scrubbers, and a world where CO2 is used as a valuable industrial input rather than emitted as a green house gas. Green Chemists are making this vision a reality.Biopesticides are a set of tools and applications that can help farmers transition away from highly toxic conventional chemical pesticides into an era of truly sustainable agriculture. Biopesticides of course are only a part of a larger solution; sustainable agriculture is a wide field. But helping farmers move from the current chemical dependency to sustainable agriculture and beyond requires tools for the transition and for a new era. Biopesticides can and will play a significant role in this process.
Like other Green Chemistry solutions, developing safe, effective biopesticide products requires holistic thinking and multi-disciplinary approaches which are a challenge for the biopesticide industry. Turning lab discoveries into profitable business products is also daunting. This mirrors what inventors face when implementing green chemistry solutions in other sectors. What follows is a summary of conclusions:
Transparency and dialogue are essential.
Broader questions of hazard are sometimes poorly understood.
Efficacy is key.
Multi-disciplinary teams are essential for moving from active ingredient to product.
Sometimes promising green chemistry discoveries sit neglected on the shelf.
Banning bad actor chemicals can be a powerful driver.
Biopesticides offer growers both opportunities – and challenges.
Conclusion
Serious questions remain about the safety of biopesticide products from both a human and ecosystem health standpoint. Current regulations do not go nearly far enough in evaluating systemic broader impacts of biopesticides. By definition, Green Chemistry is about continuous improvements aimed at reducing or eliminating hazard. Fully defining hazard is difficult. Even products hailed by Green Chemists and regulators alike as safer for human health may turn out to have unforeseen negative environmental health impacts. See for example, Spinosad, a green chemistry award winning biopesticide, which while significantly safer for humans than other pesticides but is toxic to bees.
We must encourage pest management solutions and regulations to continuously evolve. We must also ensure that multi-disciplinary teams, including Green Chemists, environmental health specialists and other scientists, approach these innovations holistically.
Biopesticides – Examples
Biopesticides offer powerful tools to create a new generation of sustainable agriculture products. They are the most likely source for alternatives to some of the most problematic chemical pesticides currently in use. Biopesticides also offer solutions to concerns such as pest resistance to traditional chemical pesticides, public concern about side effects of pesticides on the surrounding environment and ultimately, on human health.
The overriding challenge for the biopesticides industry is to live up to the promise that the field holds. There are unanswered questions and un-examined assumptions about them with which those involved must contend. Challenges to biopesticides stem from questions about their efficacy and safety, public and grower confusion about the spectrum of biopesticide products on the market, and current market conditions that paradoxically both hinder and favor the field’s growth.
These stories highlight some of the successes and challenges for expanding use of biopesticides.
The Challenge of Commercialization for Niche Products. A look at economic and regulatory challenges and opportunities impacting commercialization of biopesticides alternatives due to their niche market applications.
Mating Disruption as a Pest Managment Tool. This example demonstrates the complexity of both developing and using biopesticides
An Alternative to Methyl Bromide: “Pasteuria” for Nematode Control. A technological advance significantly decreased the cost of production, making the product economically viable.
Large-scale Production of Baculovirus Isolate. A look at the greater production complexity (and potential costs) of developing a biopesticide.
The Challenges of Product Formulation, Proprietary Ingredients and Community Dialogue: The Light Brown Apple Moth. Success for the field of biopesticides will require greater transparency in research, design, and application.
Niche Marketing as an Opportunity for Competitive Differentiation “Bioworks”. This case illustrates how biopesticide companies can position themselves for success within a shifting paradigm.
Codling Moth Control- Regulatory Changes Can Drive Innovation (and Lack of Regulation Can Stymie It). Shifting to more sustainable agricultural practices rarely is as simple as a one to one replacement of an existing pesticide.



